MetaCyc Pathway: ethylbenzene degradation (anaerobic) in Pseudomonas simiae WCS417

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Reactions and Genes 2-Deoxy-D-ribonic lithium salt 10 mM (C)
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Ethylbenzene hydroxylase:
ethylbenzene + an oxidized electron carrier + H2O→(S)-1-phenylethanol + a reduced two electron carrier (EC 1.17.99.2)
No genes
(S)-1-phenylethanol + NAD+→acetophenone + NADH + H+ (EC 1.1.1.311)
No genes
acetophenone + 2 ATP + hydrogen carbonate + H2O→3-oxo-3-phenylpropanoate + 2 ADP + 2 H+ + 2 phosphate (EC 6.4.1.8)
No genes
3-oxo-3-phenylpropanoate + ATP + coenzyme A→3-oxo-3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
Acetyl-CoA C-acyltransferase (in reverse):
3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
PS417_06710 -0.6
PS417_07580 N.D.
PS417_10515 -3.8
PS417_13855 +0.4
PS417_15175 N.D.
PS417_19210 -0.2
PS417_21220 -0.3
PS417_03145 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information