MetaCyc Pathway: L-lysine degradation X in Pseudomonas putida KT2440

Add experiment(s):


Reactions and Genes 5-Aminovaleric 10 mM (C)
remove
Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
PP_0864 -0.0
PP_4140 +0.2
Putrescine aminotransferase:
cadaverine + 2-oxoglutarate→5-aminopentanal + L-glutamate (EC 2.6.1.82)
No genes
Aminobutyraldehyde dehydrogenase:
5-aminopentanal + NAD+ + H2O→5-aminopentanoate + NADH + 2 H+ (EC 1.2.1.19)
PP_1481 -0.0
PP_2801 -0.0
5-aminovalerate transaminase:
5-aminopentanoate + 2-oxoglutarate→glutarate semialdehyde + L-glutamate (EC 2.6.1.48)
PP_0214 -3.4
Glutarate-semialdehyde dehydrogenase:
glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+ (EC 1.2.1.20)
PP_0213 -4.0
PP_3151 -0.8
PP_4422 +0.7
Succinate--hydroxymethylglutarate CoA-transferase:
glutarate + succinyl-CoA→glutaryl-CoA + succinate (EC 2.8.3.13)
PP_0159 -1.4

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information