MetaCyc Pathway: L-tryptophan degradation X (mammalian, via tryptamine) in Pseudomonas putida KT2440

Reactions and Genes	L-Lysine 10 mM (C)
L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
PP_2552	+0.1
Monoamine oxidase: tryptamine + dioxygen + H2O→(indol-3-yl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
PP_4983	+0.1
Indole-3-acetaldehyde reductase (NADPH) (in reverse): (indol-3-yl)acetaldehyde + NADPH + H+→(indol-3-yl)ethanol + NADP+ (EC 1.1.1.191; 1.1.1.2)
No genes
Aldehyde dehydrogenase (NAD(+)): (indol-3-yl)acetaldehyde + NAD+ + H2O→(indol-3-yl)acetate + NADH + 2 H+ (EC 1.2.1.3)
PP_0545	+0.2
PP_0665	+0.1
PP_0708	-0.0
PP_1948	+0.0
PP_2487	-0.2
PP_2589	+0.4
PP_2680	+0.0
PP_2694	+0.2
PP_3270	+0.0
PP_3463	+0.0
PP_3646	-0.3
PP_5258	-4.6
PP_5278	+0.4
PP_5372	-0.2

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information