MetaCyc Pathway: L-lysine degradation I in Pseudomonas putida KT2440

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Reactions and Genes 5-Aminovaleric 10 mM (C)
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Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
PP_0864 -0.1
PP_4140 -0.3
Putrescine aminotransferase:
cadaverine + 2-oxoglutarate→5-aminopentanal + L-glutamate (EC 2.6.1.82)
No genes
Aminobutyraldehyde dehydrogenase:
5-aminopentanal + NAD+ + H2O→5-aminopentanoate + NADH + 2 H+ (EC 1.2.1.19)
PP_1481 -0.4
PP_2801 -0.2
5-aminovalerate transaminase:
2-oxoglutarate + 5-aminopentanoate→glutarate semialdehyde + L-glutamate (EC 2.6.1.48)
PP_0214 -2.6
Glutarate-semialdehyde dehydrogenase:
glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+ (EC 1.2.1.20)
PP_0213 -3.0
PP_3151 -0.5
PP_4422 +0.8
2-oxoglutarate + glutarate + dioxygen→(S)-2-hydroxyglutarate + CO2 + succinate (EC 1.14.11.64)
PP_2909 -2.2
(S)-2-hydroxyglutarate + an electron-transfer quinone→2-oxoglutarate + an electron-transfer quinol (EC 1.1.5.13)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information