MetaCyc Pathway: arsenate detoxification I in Agrobacterium fabrum C58

Reactions and Genes	Lactulose (C)
	remove
arsenate_[out] + ATP_[in] + H₂O_[in]→arsenate_[in] + ADP_[in] + H⁺_[in] + phosphate_[in] (EC 7.3.2.1)
Atu0423	N.D.
arsenate_[out] + H⁺_[out]→arsenate_[in] + H⁺_[in]
No genes
Arsenate reductase (glutaredoxin): arsenate + glutathione + 2 H⁺ + a reduced glutaredoxin→arsenous acid + a [glutaredoxin]-glutathione disulfide + H₂O (EC 1.20.4.1)
Atu0535	-1.5
Atu1490	-0.1
Atu1492	+0.0
arsenous acid + 3 glutathione→arsenic triglutathione + 3 H₂O (spontaneous)
No genes
arsenic triglutathione + an [ArsD arsenite metallochaperone]→an arsenite-[ArsD arsenite metallochaperone] complex + 3 glutathione
No genes
an arsenite-[ArsD arsenite metallochaperone] complex_[in] + ATP_[in] + 4 H₂O_[in]→arsenous acid_[out] + ADP_[in] + an [ArsD arsenite metallochaperone]_[in] + H⁺_[in] + phosphate_[in] (EC 7.3.2.7)
No genes

Links:

Pathway details at MetaCyc
Fitness data for 4 genes
Select organism:
All MetaCyc pathways for Agrobacterium fabrum C58

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information