MetaCyc Pathway: L-tryptophan degradation II (via pyruvate) in Escherichia coli ECOR27

Reactions and Genes	CM1
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Tryptophanase: L-tryptophan→2-aminoprop-2-enoate + indole (EC 4.1.99.1)
NOLOHH_07115 (tnaA)	-0.1
Tryptophanase: 2-aminoprop-2-enoate→2-iminopropanoate (spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
NOLOHH_07115 (tnaA)	-0.1
NOLOHH_10205 (tdcG)	-0.1
NOLOHH_12055 (sdaB)	-1.9
NOLOHH_14130 (dsdA)	-0.0
NOLOHH_16415 (dcyD)	+0.1
NOLOHH_17070 (sdaA)	-0.3
2-iminopropanoate + H₂O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
NOLOHH_04135 (ridA)	+0.1
NOLOHH_07115 (tnaA)	-0.1
NOLOHH_10200 (tdcF)	-1.5
NOLOHH_10205 (tdcG)	-0.1
NOLOHH_12055 (sdaB)	-1.9
NOLOHH_14130 (dsdA)	-0.0
NOLOHH_16415 (dcyD)	+0.1
NOLOHH_17070 (sdaA)	-0.3

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Pathway details at MetaCyc
Fitness data for 8 genes
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All MetaCyc pathways for Escherichia coli ECOR27

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information