MetaCyc Pathway: superpathway of glycol metabolism and degradation in Pseudomonas sp. RS175

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Reactions and Genes Guanosine (C)
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Lactaldehyde reductase:
ethylene glycol + NAD+→glycolaldehyde + NADH + H+ (EC 1.1.1.77)
No genes
Glycolaldehyde dehydrogenase:
glycolaldehyde + NAD+ + H2O→glycolate + NADH + 2 H+ (EC 1.2.1.21)
PFR28_01819 -0.3
PFR28_01935 -0.3
PFR28_03885 -0.5
PFR28_04407 -0.1
Glycolate dehydrogenase:
glycolate[in] + an electron-transfer quinone→glyoxylate[in] + an electron-transfer quinol (EC 1.1.99.14)
PFR28_01530 +0.0
PFR28_02758 +0.1
PFR28_02759 -0.5
PFR28_02760 -0.2
Tartronate-semialdehyde synthase:
2 glyoxylate + H+→(2R)-tartronate semialdehyde + CO2 (EC 4.1.1.47)
PFR28_03110 -1.5
Malate synthase:
glyoxylate + acetyl-CoA + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9)
PFR28_04110 -0.7
2-hydroxy-3-oxopropionate reductase (in reverse):
(2R)-tartronate semialdehyde + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.60)
PFR28_02164 -0.4
PFR28_03112 N.D.
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
PFR28_02469 -1.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information