MetaCyc Pathway: 3-methyl-branched fatty acid α-oxidation in Pseudomonas sp. RS175

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Reactions and Genes octanoate (C)
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Long-chain-fatty-acid--CoA ligase:
a 3-methyl-branched 2,3,4-saturated fatty acid + ATP + coenzyme A→a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate
(EC 6.2.1.3)
PFR28_00584 -0.0
PFR28_00585 -2.7
PFR28_01261 -0.0
PFR28_03122 -0.2
a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + 2-oxoglutarate + dioxygen→a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA + CO2 + succinate
No genes
a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA→a 2-methyl branched 2,3,4-saturated fatty aldehyde + formyl-CoA (EC 4.1.2.63)
No genes
Formyl-CoA hydrolase:
formyl-CoA + H2O→formate + coenzyme A + H+
(EC 3.1.2.10)
No genes
Aldehyde dehydrogenase (NAD(+)):
a 2-methyl branched 2,3,4-saturated fatty aldehyde + NAD+ + H2O→a 2-methyl branched 2,3,4-saturated fatty acid + NADH + 2 H+
(EC 1.2.1.3)
PFR28_00143 +0.2
PFR28_01819 +0.3
PFR28_01935 -0.3
PFR28_01983 +0.2
PFR28_03885 -0.0
PFR28_04266 +0.1
PFR28_04407 -0.2
PFR28_05151 -0.1
Long-chain-fatty-acid--CoA ligase:
a 2-methyl branched 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2-methyl branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate
(EC 6.2.1.3)
PFR28_00584 -0.0
PFR28_00585 -2.7
PFR28_01261 -0.0
PFR28_03122 -0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information