MetaCyc Pathway: fatty acid β-oxidation I (generic) in Pseudomonas putida KT2440

Add experiment(s):


Reactions and Genes Vanillic Acid (C)
remove
a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Dodecenoyl-CoA isomerase:
a (3Z)-3-enoyl-CoA→a (2E)-2-enoyl-CoA
(EC 5.3.3.8)
PP_2047 +0.0
PP_2136 +0.1
3-hydroxybutyryl-CoA epimerase:
a 2,3,4-saturated (3R)-3-hydroxyacyl-CoA→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 5.1.2.3)
PP_2047 +0.0
PP_2136 +0.1
a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+→a (2E)-2-enoyl-CoA + a reduced electron-transfer flavoprotein
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
PP_1412 -0.2
PP_1845 +0.0
PP_2047 +0.0
PP_2136 +0.1
PP_2217 -1.9
PP_3283 -0.0
PP_3284 -0.3
PP_3358 -0.1
PP_3491 -0.3
PP_3726 +0.3
PP_3732 -0.1
PP_4030 +0.2
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
PP_2047 +0.0
PP_2136 +0.1
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
PP_0582 +0.1
PP_1377 -2.9
PP_2051 -0.2
PP_2137 +0.2
PP_2215 -1.1
PP_3280 -0.2
PP_3355 +0.2
PP_3754 -0.2
PP_4636 +0.3

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information