MetaCyc Pathway: aminopropylcadaverine biosynthesis in Escherichia coli BW25113

Reactions and Genes	LMW_DNA_from_Pseudomonas_EB271-B4-1 12 ppm (C)
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Lysine decarboxylase: L-lysine + H⁺→cadaverine + CO₂ (EC 4.1.1.18)
b0186 (ldcC)	-0.1
b4131 (cadA)	-0.1
Adenosylmethionine decarboxylase: S-adenosyl-L-methionine + H⁺→S-adenosyl 3-(methylsulfanyl)propylamine + CO₂ (EC 4.1.1.50)
b0120 (speD)	+1.8
cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine→aminopropylcadaverine + S-methyl-5'-thioadenosine + H⁺
b0121 (speE)	+2.3

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Pathway details at MetaCyc
Fitness data for 4 genes
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All MetaCyc pathways for Escherichia coli BW25113

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information