MetaCyc Pathway: superpathway of polyamine biosynthesis I in Escherichia coli BW25113

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Reactions and Genes LMW_DNA_from_Pseudomonas_EB271-B4-1 12 ppm (C)
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Arginine decarboxylase:
L-arginine + H+→agmatine + CO2
(EC 4.1.1.19)
b2938 (speA) -0.2
b4117 (adiA) +0.0
Arginase:
L-arginine + H2O→L-ornithine + urea
(EC 3.5.3.1)
No genes
Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2
(EC 4.1.1.18)
b0186 (ldcC) -0.1
b4131 (cadA) -0.1
Adenosylmethionine decarboxylase:
S-adenosyl-L-methionine + H+S-adenosyl 3-(methylsulfanyl)propylamine + CO2
(EC 4.1.1.50)
b0120 (speD) +1.8
Agmatinase:
agmatine + H2O→putrescine + urea
(EC 3.5.3.11)
b2937 (speB) +0.0
Ornithine decarboxylase:
L-ornithine + H+→putrescine + CO2
(EC 4.1.1.17)
b0693 (speF) -0.0
b2965 (speC) +0.0
cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine→aminopropylcadaverine + S-methyl-5'-thioadenosine + H+
b0121 (speE) +2.3
Spermidine synthase:
putrescine + S-adenosyl 3-(methylsulfanyl)propylamine→spermidine + S-methyl-5'-thioadenosine + H+
(EC 2.5.1.16)
b0121 (speE) +2.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information