MetaCyc Pathway: arsenic detoxification (plants) in Escherichia coli BW25113

Reactions and Genes	HMW_DNA_from_Pseudomonas_EB271-B4-1 46.9 ppm (C)
	remove
arsenate_[out] + H⁺_[out]→arsenate_[in] + H⁺_[in]
b2987 (pitB)	-0.1
b3493 (pitA)	-0.1
arsenous acid_[out]→arsenous acid_[in]
b3927 (glpF)	-1.7
Arsenate reductase (glutaredoxin): arsenate + glutathione + 2 H⁺ + a reduced glutaredoxin→arsenous acid + a [glutaredoxin]-glutathione disulfide + H₂O (EC 1.20.4.1)
b2495 (yfgD)	+0.5
b3503 (arsC)	-0.1
arsenous acid + phytochelatin 3→arsenic-phytochelatin 3 + 3 H₂O (spontaneous)
No genes
arsenous acid_[in] + H⁺_[out]→arsenous acid_[out] + H⁺_[in]
b3502 (arsB)	+0.0
arsenic-phytochelatin 3_[in] + ATP_[in] + H₂O_[in]→arsenic-phytochelatin 3_[out] + ADP_[in] + H⁺_[in] + phosphate_[in] (EC 7.6.2.3)
No genes

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Pathway details at MetaCyc
Fitness data for 6 genes
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All MetaCyc pathways for Escherichia coli BW25113

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information