MetaCyc Pathway: superpathway of glyoxylate cycle and fatty acid degradation in Bosea sp. OAE506

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Reactions and Genes Ying_all64 rep B; time point 3
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a 2,3,4-saturated fatty acid + ATP + coenzyme A→a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate
No genes
Acyl-CoA oxidase:
a 2,3,4-saturated fatty acyl CoA + dioxygen→a (2E)-2-enoyl-CoA + hydrogen peroxide
(EC 1.3.3.6)
No genes
Enoyl-CoA hydratase (in reverse):
a (2E)-2-enoyl-CoA + H2O→a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA
(EC 4.2.1.17)
ABIE41_RS04195 -0.5
ABIE41_RS07775 -0.0
ABIE41_RS07780 -0.0
ABIE41_RS10405 -0.1
ABIE41_RS16295 +0.4
ABIE41_RS17285 -0.6
ABIE41_RS18700 -0.3
ABIE41_RS19240 +0.2
ABIE41_RS19820 -1.1
ABIE41_RS20600 N.D.
ABIE41_RS23310 -0.2
3-hydroxyacyl-CoA dehydrogenase:
a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA + NAD+→a 2,3,4-saturated 3-oxoacyl-CoA + NADH + H+
(EC 1.1.1.35)
ABIE41_RS07780 -0.0
ABIE41_RS12780 +0.0
ABIE41_RS18595 -0.2
ABIE41_RS23310 -0.2
Acetyl-CoA C-acyltransferase (in reverse):
a 2,3,4-saturated 3-oxoacyl-CoA + coenzyme A→a 2,3,4-saturated fatty acyl CoA + acetyl-CoA
(EC 2.3.1.16)
ABIE41_RS07785 -1.6
ABIE41_RS07970 +0.3
ABIE41_RS08710 N.D.
ABIE41_RS23315 -0.4
Citrate (Si)-synthase:
acetyl-CoA + oxaloacetate + H2O→citrate + coenzyme A + H+
(EC 2.3.3.1; 2.3.3.16; 2.3.3.3)
ABIE41_RS17520 N.D.
Aconitate hydratase:
citrate→cis-aconitate + H2O
(EC 4.2.1.3)
ABIE41_RS04965 N.D.
Aconitate hydratase:
cis-aconitate + H2O→D-threo-isocitrate
(EC 4.2.1.3)
ABIE41_RS04965 N.D.
Isocitrate lyase:
D-threo-isocitrate→glyoxylate + succinate
(EC 4.1.3.1)
ABIE41_RS16605 +0.0
Malate synthase:
acetyl-CoA + glyoxylate + H2O→(S)-malate + coenzyme A + H+
(EC 2.3.3.9)
ABIE41_RS09675 +0.1
Succinate dehydrogenase (ubiquinone):
succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol
(EC 1.3.5.1)
ABIE41_RS05745 N.D.
Fumarate hydratase (in reverse):
fumarate + H2O→(S)-malate
(EC 4.2.1.2)
ABIE41_RS00110 -0.3
ABIE41_RS12805 N.D.
Malate dehydrogenase:
(S)-malate + NAD+→oxaloacetate + NADH + H+
(EC 1.1.1.37; 1.1.1.38)
ABIE41_RS08960 N.D.
ABIE41_RS16945 -0.4
Phosphoenolpyruvate carboxykinase (ATP):
oxaloacetate + ATP→phosphoenolpyruvate + ADP + CO2
(EC 4.1.1.49)
ABIE41_RS02665 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information