MetaCyc Pathway: 8-amino-7-oxononanoate biosynthesis IV in Pseudomonas simiae WCS417

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Reactions and Genes nitrate (N)
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glutaryl-CoA + a malonyl-[acp] + H+→a 3-oxopimeloyl-[acp] + CO2 + coenzyme A
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxopimeloyl-[acp] + NADPH + H+→a (3R)-3-hydroxypimeloyl-[acp] + NADP+ (EC 1.1.1.100)
PS417_05265 N.D.
PS417_05270 +0.3
PS417_11810 +0.6
PS417_01365 N.D.
PS417_13755 +0.6
PS417_15185 +0.1
PS417_16870 +0.3
PS417_17710 N.D.
PS417_17895 N.D.
PS417_02035 +0.0
PS417_21145 -0.1
PS417_21340 +0.1
PS417_21440 N.D.
PS417_03140 +0.2
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxypimeloyl-[acp]→a 2-enoyl-pimeloyl-[acp] + H2O (EC 4.2.1.59)
PS417_06265 N.D.
PS417_08980 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a 2-enoyl-pimeloyl-[acp] + NADH + H+→a pimeloyl-[acp] + NAD+ (EC 1.3.1.9)
PS417_14110 +0.0
8-amino-7-oxononanoate synthase:
a pimeloyl-[acp] + L-alanine + H+→(8S)-8-amino-7-oxononanoate + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.47)
PS417_26000 -3.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information