MetaCyc Pathway: superpathway of purines degradation in plants in Pseudomonas simiae WCS417

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Reactions and Genes Inosine (N)
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Adenosine-phosphate deaminase:
AMP + H+ + H2O→IMP + ammonium (EC 3.5.4.17; 3.5.4.6)
No genes
5'-nucleotidase:
GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
PS417_06350 -0.6
PS417_08450 -0.2
PS417_01285 +0.4
Guanosine deaminase:
guanosine + H+ + H2O→xanthosine + ammonium (EC 3.5.4.15)
No genes
IMP dehydrogenase:
IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
PS417_10545 N.D.
PS417_23075 N.D.
5'-nucleotidase:
IMP + H2O→inosine + phosphate (EC 3.1.3.5; 3.1.3.99)
PS417_06350 -0.6
PS417_08450 -0.2
PS417_01285 +0.4
Purine nucleosidase:
guanosine + H2O→guanine + D-ribofuranose (EC 3.2.2.1)
PS417_12990 +0.1
PS417_18375 +0.1
Guanine deaminase:
guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
PS417_20900 -0.1
PS417_03215 +0.0
Inosine nucleosidase:
inosine + H2O→hypoxanthine + D-ribofuranose (EC 3.2.2.2)
PS417_12990 +0.1
PS417_18375 +0.1
5'-nucleotidase:
XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
PS417_06350 -0.6
PS417_08450 -0.2
Xanthine dehydrogenase:
hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
PS417_20885 -0.9
PS417_20890 -0.9
PS417_24360 +0.0
PS417_24365 +0.2
Purine nucleosidase:
xanthosine + H2O→xanthine + D-ribofuranose (EC 3.2.2.1)
PS417_12990 +0.1
PS417_18375 +0.1
Xanthine dehydrogenase:
xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
PS417_20885 -0.9
PS417_20890 -0.9
PS417_24360 +0.0
PS417_24365 +0.2
Urate oxidase:
urate + dioxygen + H2O→(S)-5-hydroxyisourate + hydrogen peroxide (EC 1.7.3.3)
PS417_06745 -0.1
PS417_19415 -3.4
PS417_19435 -1.2
PS417_04855 +0.0
Hydroxyisourate hydrolase:
(S)-5-hydroxyisourate + H2O→(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+ (EC 3.5.2.17)
PS417_19410 N.D.
(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline + H+→(S)-(+)-allantoin + CO2 (EC 4.1.1.97)
No genes
Allantoinase:
(S)-(+)-allantoin + H2O→allantoate + H+ (EC 3.5.2.5)
No genes
Allantoicase:
allantoate + H2O→(S)-ureidoglycolate + urea (EC 3.5.3.4)
PS417_19425 -2.7
Ureidoglycolate lyase:
(S)-ureidoglycolate→glyoxylate + urea (EC 4.3.2.3)
PS417_19430 -1.7

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information