MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Pseudomonas simiae WCS417

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Reactions and Genes Adenine (N)
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Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
PS417_07385 -0.1
PS417_14475 -0.0
PS417_15020 +0.1
PS417_27040 -6.5
PS417_04530 +0.6
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
PS417_08120 N.D.
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
PS417_09335 -0.0
PS417_21120 -2.7
PS417_21770 N.D.
PS417_02415 -3.0
PS417_26895 +0.1
PS417_26995 -3.8
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O (EC 2.1.2.1)
PS417_24275 +0.3
PS417_24280 N.D.
PS417_26195 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information