| Reactions and Genes | R2A with Vancomycin 0.009 mM |
|---|
| remove |
Peptidoglycan glycosyltransferase:
Und-PP-[β-D-GlcNAc-(1→4)]-MurNAc-L-Ala-γ-D-Glu-meso-DAP-D-Ala-D-Ala + a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide→a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + di-trans,octa-cis-undecaprenyl diphosphate (EC 2.4.1.129) |
| Atu0103 | -3.0 |
| Atu0931 | +3.6 |
| Atu1067 | -0.5 |
| Atu1341 | N.D. |
| Atu2100 | N.D. |
| Atu3694 | -0.1 |
Serine-type D-Ala-D-Ala carboxypeptidase:
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + H2O→a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + D-alanine (EC 3.4.16.4) |
| Atu1499 | +1.3 |
| Atu1505 | N.D. |
| Atu2321 | +0.1 |
| Atu2513 | -0.2 |
| Atu3634 | +7.3 |
Serine-type D-Ala-D-Ala carboxypeptidase:
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + a peptidoglycan internal segment with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide→a nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine (EC 3.4.16.4) |
| Atu1499 | +1.3 |
| Atu1505 | N.D. |
| Atu2321 | +0.1 |
| Atu2513 | -0.2 |
| Atu3634 | +7.3 |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide→a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + a peptidoglycan internal segment with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide→a nascent peptidoglycan with L,D cross links (meso-diaminopimelate containing) + D-alanine |
| No genes |
Muramoyltetrapeptide carboxypeptidase:
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + H2O→a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide + D-alanine (EC 3.4.17.13) |
| No genes |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + glycine→a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide + D-alanine |
| No genes |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide→a mature peptidoglycan (with L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine tetrapeptide) + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing)→a mature peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide→a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with L,D cross links (meso-diaminopimelate containing)→a mature peptidoglycan with L,D cross-links (meso-diaminopimelate containing) + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
| a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide→a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide + H+ + di-trans,octa-cis-undecaprenyl diphosphate |
| No genes |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information