MetaCyc Pathway: glyphosate degradation III in Agrobacterium fabrum C58

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Reactions and Genes R2A with Phosphomycin 50 mM
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glyphosate + ATP→α-D-ribose-1-[N-(phosphonomethyl)glycine] 5-triphosphate + adenine + H+ (EC 2.7.8.37)
Atu0179 -1.1
α-D-ribose-1-[N-(phosphonomethyl)glycine] 5-triphosphate + H2O→α-D-ribose-1-[N-(phosphonomethyl)glycine] 5-phosphate + diphosphate + H+ (EC 3.6.1.63)
Atu0169 -5.8
α-D-ribose-1-[N-(phosphonomethyl)glycine] 5-phosphate + a reduced two electron carrier + S-adenosyl-L-methionine→5-phospho-α-D-ribose 1,2-cyclic phosphate + an oxidized electron carrier + 5'-deoxyadenosine + L-methionine + sarcosine (EC 4.7.1.1)
Atu0178 -1.2
5-phospho-α-D-ribose 1,2-cyclic phosphate + H2O→α-D-ribose 1,5-bisphosphate + H+ (EC 3.1.4.55)
Atu2329 -0.0
Ribose 1,5-bisphosphate phosphokinase:
α-D-ribose 1,5-bisphosphate + ATP→5-phospho-α-D-ribose 1-diphosphate + ADP (EC 2.7.4.23)
Atu0168 +0.1
Adenine phosphoribosyltransferase (in reverse):
5-phospho-α-D-ribose 1-diphosphate + adenine→diphosphate + AMP (EC 2.4.2.7)
Atu2236 -0.2
Inorganic diphosphatase:
diphosphate + H2O→2 phosphate + H+ (EC 3.6.1.1)
Atu1174 +0.0
Atu2661 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information