MetaCyc Pathway: superpathway of guanosine nucleotides de novo biosynthesis I in Agrobacterium fabrum C58

Reactions and Genes	R2A with m-arsenite 0.8 mM
IMP dehydrogenase: IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
Atu0624	N.D.
GMP synthase (glutamine-hydrolyzing): XMP + ATP + L-glutamine + H2O→GMP + AMP + L-glutamate + diphosphate + 2 H+ (EC 6.3.5.2)
Atu0281	N.D.
Atu2658	+0.1
Guanylate kinase: GMP + ATP→GDP + ADP (EC 2.7.4.8)
Atu0168	-0.1
Atu1101	N.D.
Nucleoside-diphosphate kinase: GDP + ATP→GTP + ADP (EC 2.7.4.6)
Atu1122	N.D.
Ribonucleoside-diphosphate reductase (in reverse): GDP + a reduced thioredoxin→dGDP + an oxidized thioredoxin + H2O (EC 1.17.4.1)
Atu0069	N.D.
Atu0070	-1.6
Atu0071	-0.9
Atu1733	N.D.
Nucleoside-diphosphate kinase: dGDP + ATP→dGTP + ADP (EC 2.7.4.6)
Atu1122	N.D.

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information