MetaCyc Pathway: anaerobic energy metabolism (invertebrates, mitochondrial) in Escherichia coli BW25113

Reactions and Genes	Ying_OrganicAcid7 rep C; time point 3
Malate dehydrogenase (oxaloacetate-decarboxylating): (S)-malate + NAD+→CO2 + pyruvate + NADH (EC 1.1.1.38)
b1479 (sfcA)	-1.2
Fumarate hydratase: (S)-malate→fumarate + H2O (EC 4.2.1.2)
b1611 (fumC)	+0.2
b1612 (fumA)	+0.1
b1675 (ydhZ)	-0.5
b2929 (yggD)	-0.0
b4122 (fumB)	-0.0
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
b0114 (aceE)	-2.2
b0115 (aceF)	N.D.
b0116 (lpd)	N.D.
Succinate dehydrogenase (ubiquinone) (in reverse): fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
No genes
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
b2920 (ygfH)	+0.3
Methylmalonyl-CoA mutase (in reverse): succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
b2917 (yliK)	-0.1
Succinate--CoA ligase (ADP-forming) (in reverse): succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
b0728 (sucC)	-2.5
b0729 (sucD)	-4.3
Methylmalonyl-CoA epimerase: (R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes
Propionyl-CoA carboxylase (in reverse): (S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
b0185 (accA)	N.D.
b2316 (accD)	N.D.

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information