MetaCyc Pathway: L-tyrosine degradation V (reductive Stickland reaction) in Escherichia coli BW25113

Reactions and Genes	Ying_OrganicAcid7 rep B; time point 3
Aspartate transaminase: L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
b0928 (aspC)	-0.8
b2021 (hisC)	-9.0
b4054 (tyrB)	-2.4
b4340 (yjiR)	-0.0
Indolelactate dehydrogenase (in reverse): 3-(4-hydroxyphenyl)pyruvate + NADH + H+→(R)-3-(4-hydroxyphenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Cinnamoyl-CoA:phenyllactate CoA-transferase: (R)-3-(4-hydroxyphenyl)lactate + (E)-4-coumaroyl-CoA→4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA (EC 2.8.3.17)
No genes
4-coumarate + a reduced electron-transfer flavoprotein→phloretate + an oxidized electron-transfer flavoprotein + H+ (EC 1.3.8.15)
No genes
(R)-3-(4-hydroxyphenyl)lactoyl-CoA→(E)-4-coumaroyl-CoA + H2O (EC 4.2.1.175)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information