MetaCyc Pathway: purine nucleotides degradation I (plants) in Escherichia coli BW25113

Reactions and Genes	M9 Anaerobic Capecitabine 500 uM
Adenosine-phosphate deaminase: AMP + H+ + H2O→IMP + ammonium (EC 3.5.4.17; 3.5.4.6)
No genes
5'-nucleotidase: GMP + H2O→guanosine + phosphate (EC 3.1.3.5)
b0480 (ushA)	+0.1
b2291 (yfbR)	+0.1
b2744 (surE)	-0.3
b3399 (yrfG)	-0.0
b4055 (aphA)	-0.0
b4374 (yjjG)	-1.2
Guanosine deaminase: guanosine + H+ + H2O→xanthosine + ammonium (EC 3.5.4.15)
No genes
IMP dehydrogenase: IMP + NAD+ + H2O→XMP + NADH + H+ (EC 1.1.1.205)
b2508 (guaB)	N.D.
5'-nucleotidase: IMP + H2O→inosine + phosphate (EC 3.1.3.5; 3.1.3.99)
b0383 (phoA)	-0.0
b0480 (ushA)	+0.1
b2291 (yfbR)	+0.1
b2744 (surE)	-0.3
b3399 (yrfG)	-0.0
b4055 (aphA)	-0.0
b4374 (yjjG)	-1.2
Purine nucleosidase: guanosine + H2O→guanine + D-ribofuranose (EC 3.2.2.1)
b0030 (rihC)	-0.1
b0651 (rihA)	-0.1
b2162 (rihB)	+0.1
Guanine deaminase: guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3)
b2883 (guaD)	-0.1
Inosine nucleosidase: inosine + H2O→hypoxanthine + D-ribofuranose (EC 3.2.2.2)
b0030 (rihC)	-0.1
b0651 (rihA)	-0.1
b2162 (rihB)	+0.1
5'-nucleotidase: XMP + H2O→xanthosine + phosphate (EC 3.1.3.5)
b0480 (ushA)	+0.1
b2291 (yfbR)	+0.1
b2744 (surE)	-0.3
b4055 (aphA)	-0.0
b4374 (yjjG)	-1.2
Xanthine dehydrogenase: hypoxanthine + NAD+ + H2O→xanthine + NADH + H+ (EC 1.17.1.4)
b0284 (yagR)	+0.1
b0285 (yagS)	+0.1
b2866 (xdhA)	+0.1
b2867 (xdhB)	-0.0
b2868 (xdhC)	+0.0
Purine nucleosidase: xanthosine + H2O→xanthine + D-ribofuranose (EC 3.2.2.1)
b0030 (rihC)	-0.1
b0651 (rihA)	-0.1
b2162 (rihB)	+0.1
Xanthine dehydrogenase: xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4)
b0284 (yagR)	+0.1
b0285 (yagS)	+0.1
b2866 (xdhA)	+0.1
b2867 (xdhB)	-0.0
b2868 (xdhC)	+0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information