MetaCyc Pathway: superpathway of pyrimidine ribonucleosides salvage in Escherichia coli BW25113

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Reactions and Genes M9 Anaerobic Capecitabine 5000 uM
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Cytidine deaminase:
cytidine + H+ + H2O→uridine + ammonium
(EC 3.5.4.5)
b2143 (cdd) +1.6
cytidine + ATP→CMP + ADP + H+ (EC 2.7.1.213; 2.7.1.48)
b2066 (udk) -0.1
Cytidylate kinase:
CMP + ATP→CDP + ADP
(EC 2.7.4.14; 2.7.4.25)
b0910 (cmk) N.D.
Uridine nucleosidase:
uridine + H2O→uracil + D-ribofuranose
(EC 3.2.2.3)
b0030 (rihC) -0.2
b0651 (rihA) +0.1
b2162 (rihB) -0.4
Uridine kinase:
uridine + ATP→UMP + ADP + H+
(EC 2.7.1.48)
b2066 (udk) -0.1
Nucleoside-diphosphate kinase:
CDP + ATP→CTP + ADP
(EC 2.7.4.6)
b0474 (adk) N.D.
b2518 (ndk) -0.1
Uracil phosphoribosyltransferase (in reverse):
uracil + 5-phospho-α-D-ribose 1-diphosphate→UMP + diphosphate
(EC 2.4.2.9)
b2498 (upp) +7.4
Cytidylate kinase:
UMP + ATP→UDP + ADP
(EC 2.7.4.14; 2.7.4.22)
b0171 (pyrH) N.D.
b0910 (cmk) N.D.
Nucleoside-diphosphate kinase:
UDP + ATP→UTP + ADP
(EC 2.7.4.6)
b0474 (adk) N.D.
b2518 (ndk) -0.1
CTP synthase:
UTP + ATP + L-glutamine + H2O→CTP + ADP + L-glutamate + 2 H+ + phosphate
(EC 6.3.4.2)
b2780 (pyrG) N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information