MetaCyc Pathway: L-proline biosynthesis III (from L-ornithine) in Pseudomonas sp. RS175

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Reactions and Genes L-Lysine (C) 10 mM
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Ornithine aminotransferase:
L-ornithine + 2-oxoglutarate→L-glutamate 5-semialdehyde + L-glutamate (EC 2.6.1.13)
PFR28_03283 +5.2
L-glutamate 5-semialdehyde→(S)-1-pyrroline-5-carboxylate + H+ + H2O (spontaneous)
No genes
Pyrroline-5-carboxylate reductase (in reverse):
(S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+→L-proline + NAD(P)+ (EC 1.5.1.2)
PFR28_04243 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information