MetaCyc Pathway: L-methionine biosynthesis II in Pseudomonas fluorescens SBW25

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Reactions and Genes NAG (C)
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Homoserine kinase:
L-homoserine + ATP→O-phospho-L-homoserine + ADP + H+
(EC 2.7.1.39)
PFLU_RS00385 -0.1
PFLU_RS22735 -1.3
Cystathionine gamma-synthase:
O-phospho-L-homoserine + L-cysteine→L-cystathionine + phosphate
(EC 2.5.1.48)
PFLU_RS02250 -0.1
PFLU_RS16625 -0.3
PFLU_RS20510 -4.3
Cysteine-S-conjugate beta-lyase:
L-cystathionine→2-aminoprop-2-enoate + L-homocysteine
(EC 4.4.1.13)
No genes
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase:
L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate→L-methionine + tetrahydropteroyl tri-L-glutamate
(EC 2.1.1.14)
PFLU_RS17405 +0.0
Tryptophanase:
2-aminoprop-2-enoate→2-iminopropanoate
(spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
PFLU_RS01220 -0.7
PFLU_RS05135 +0.1
PFLU_RS12815 -1.9
PFLU_RS16625 -0.3
PFLU_RS24005 +0.1
PFLU_RS27960 +0.0
2-iminopropanoate + H2O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
PFLU_RS01220 -0.7
PFLU_RS05135 +0.1
PFLU_RS12815 -1.9
PFLU_RS16625 -0.3
PFLU_RS24005 +0.1
PFLU_RS27960 +0.0
PFLU_RS29515 -0.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information