MetaCyc Pathway: γ-linolenate biosynthesis II (animals) in Escherichia coli BW25113

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Reactions and Genes 2,4-Dinitrophenol 2 mM
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Long-chain-fatty-acid--CoA ligase:
linoleate + ATP + coenzyme A→linoleoyl-CoA + AMP + diphosphate
(EC 6.2.1.3)
b1805 (fadD) +1.1
Linoleoyl-CoA desaturase:
linoleoyl-CoA + 2 a ferrocytochrome b5 + dioxygen + 2 H+→γ-linolenoyl-CoA + 2 a ferricytochrome b5 + 2 H2O
(EC 1.14.19.3)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information