MetaCyc Pathway: superpathway of glycol metabolism and degradation in Escherichia coli BW25113

Reactions and Genes	2,4-Dinitrophenol 2 mM
Lactaldehyde reductase: ethylene glycol + NAD+→glycolaldehyde + NADH + H+ (EC 1.1.1.77)
b2799 (fucO)	-0.2
Glycolaldehyde dehydrogenase: glycolaldehyde + NAD+ + H2O→glycolate + NADH + 2 H+ (EC 1.2.1.21)
b1415 (aldA)	+0.2
Glycolate dehydrogenase: glycolate[in] + an electron-transfer quinone→glyoxylate[in] + an electron-transfer quinol (EC 1.1.99.14)
b1687 (ydiJ)	+0.0
b2979 (glcD)	-0.3
b4467 (glcF)	-0.2
b4468 (glcE)	-0.0
Tartronate-semialdehyde synthase: 2 glyoxylate + H+→(2R)-tartronate semialdehyde + CO2 (EC 4.1.1.47)
b0507 (gcl)	+0.1
Malate synthase: glyoxylate + acetyl-CoA + H2O→(S)-malate + coenzyme A + H+ (EC 2.3.3.9)
b2976 (glcB)	+0.1
b4014 (aceB)	+0.2
2-hydroxy-3-oxopropionate reductase (in reverse): (2R)-tartronate semialdehyde + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.60)
b0509 (glxR)	-0.0
b3125 (garR)	-0.0
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
b0514 (glxK)	+0.1
b3124 (garK)	-2.3

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information