MetaCyc Pathway: superpathway of pyrimidine deoxyribonucleosides degradation in Escherichia coli BW25113

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Reactions and Genes 2,4-Dinitrophenol 2 mM
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Cytidine deaminase:
2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium
(EC 3.5.4.5)
b2143 (cdd) -0.5
Pyrimidine-nucleoside phosphorylase:
thymidine + phosphate→2-deoxy-α-D-ribose 1-phosphate + thymine
(EC 2.4.2.2; 2.4.2.4)
b0391 (yaiE) -0.2
b4382 (deoA) -0.1
Pyrimidine-nucleoside phosphorylase:
2'-deoxyuridine + phosphate→2-deoxy-α-D-ribose 1-phosphate + uracil
(EC 2.4.2.2; 2.4.2.3)
b3831 (udp) -0.4
b4382 (deoA) -0.1
b4384 (deoD) -1.4
Phosphopentomutase:
2-deoxy-α-D-ribose 1-phosphate→2-deoxy-D-ribose 5-phosphate
(EC 5.4.2.7)
b3380 (yhfW) -0.3
b4383 (deoB) -2.4
Deoxyribose-phosphate aldolase:
2-deoxy-D-ribose 5-phosphate→acetaldehyde + D-glyceraldehyde 3-phosphate
(EC 4.1.2.4)
b4381 (deoC) -1.1
Acetaldehyde dehydrogenase (acetylating):
acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+
(EC 1.2.1.10)
b0351 (mhpF) -0.1
b1241 (adhE) -0.4
b2455 (eutE) -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information