MetaCyc Pathway: superpathway of guanine and guanosine salvage in Escherichia coli BW25113

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Reactions and Genes 2,4-Dinitrophenol 2 mM
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Inosine kinase:
guanosine + ATP→GMP + ADP + H+
(EC 2.7.1.73)
b0477 (gsk) -0.0
Purine-nucleoside phosphorylase:
guanosine + phosphate→guanine + α-D-ribose-1-phosphate
(EC 2.4.2.1; 2.4.2.15)
b0391 (yaiE) -0.2
b2407 (xapA) -0.0
b4384 (deoD) -1.4
Hypoxanthine phosphoribosyltransferase (in reverse):
guanine + 5-phospho-α-D-ribose 1-diphosphate→GMP + diphosphate
(EC 2.4.2.8)
b0125 (hpt) -0.6
b0238 (gpt) -0.4
b0469 (apt) -0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information