MetaCyc Pathway: benzoyl-CoA degradation I (aerobic) in Variovorax sp. OAS795

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Reactions and Genes Plant=Brachypodium_distachyon; PlantTreatment=None; Sample=soil; GrowthSubstrate=quartz_sand; Collection=outgrowth_R2A_with_Tween_and_Cycloheximide; Time=21_days
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benzoyl-CoA + NADPH + dioxygen + H+→2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O (EC 1.14.13.208)
ABID97_RS03120 -2.0
2,3-epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O→cis-3,4-dehydroadipyl-CoA semialdehyde + formate + H+ (EC 4.1.2.44)
ABID97_RS03115 -2.7
cis-3,4-dehydroadipyl-CoA semialdehyde + NADP+ + H2O→cis-3,4-dehydroadipyl-CoA + NADPH + 2 H+ (EC 1.2.1.77)
ABID97_RS03100 -0.3
cis-3,4-dehydroadipyl-CoA→(2E)-5-carboxy-2-pentenoyl-CoA
No genes
Enoyl-CoA hydratase (in reverse):
(2E)-5-carboxy-2-pentenoyl-CoA + H2O→(3S)-hydroxyadipyl-CoA (EC 4.2.1.17)
ABID97_RS00815 -0.2
ABID97_RS01435 -0.2
ABID97_RS02880 +0.3
ABID97_RS03115 -2.7
ABID97_RS04670 +0.1
ABID97_RS05865 -1.0
ABID97_RS05900 -0.2
ABID97_RS05990 +0.4
ABID97_RS06010 +0.2
ABID97_RS07755 -0.0
ABID97_RS10620 N.D.
ABID97_RS14445 -0.1
ABID97_RS15740 -0.2
ABID97_RS17005 -0.2
ABID97_RS17010 +0.2
ABID97_RS17470 +0.1
ABID97_RS18490 -0.0
ABID97_RS18595 N.D.
ABID97_RS18600 -0.6
ABID97_RS18605 N.D.
ABID97_RS18635 +0.1
ABID97_RS19410 -0.7
ABID97_RS20990 -0.1
ABID97_RS22770 +0.1
ABID97_RS24015 -0.2
ABID97_RS24805 -0.4
ABID97_RS26735 N.D.
ABID97_RS27490 +0.0
ABID97_RS27535 +1.4
ABID97_RS27555 -0.3
ABID97_RS27620 N.D.
ABID97_RS28260 N.D.
ABID97_RS28410 N.D.
ABID97_RS29050 -0.4
3-hydroxyacyl-CoA dehydrogenase:
(3S)-hydroxyadipyl-CoA + NAD+→3-oxoadipoyl-CoA + NADH + H+ (EC 1.1.1.35)
ABID97_RS03030 -0.4
ABID97_RS05865 -1.0
ABID97_RS06010 +0.2
ABID97_RS08805 +0.1
ABID97_RS10560 -0.6
ABID97_RS15740 -0.2
ABID97_RS17005 -0.2
ABID97_RS18595 N.D.
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipoyl-CoA + coenzyme A→succinyl-CoA + acetyl-CoA (EC 2.3.1.174)
ABID97_RS24190 -0.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information