MetaCyc Pathway: superpathway of L-serine and glycine biosynthesis I in Pseudomonas putida KT2440

Add experiment(s):


Reactions and Genes Formaldehyde 0.03125 vol%
remove
Phosphoglycerate dehydrogenase:
3-phospho-D-glycerate + NAD+→3-phosphooxypyruvate + NADH + H+ (EC 1.1.1.95)
PP_0762 -0.1
PP_2533 -0.0
PP_3225 +0.0
PP_4316 +0.3
PP_4589 +0.1
PP_5155 +0.3
Phosphoserine transaminase (in reverse):
3-phosphooxypyruvate + L-glutamate→O-phospho-L-serine + 2-oxoglutarate (EC 2.6.1.52)
PP_1768 N.D.
Phosphoserine phosphatase:
O-phospho-L-serine + H2O→L-serine + phosphate (EC 3.1.3.3)
PP_1721 -0.1
PP_4909 +0.0
PP_5130 -0.1
PP_5147 -0.0
Glycine hydroxymethyltransferase:
L-serine + a tetrahydrofolate→glycine + a 5,10-methylenetetrahydrofolate + H2O (EC 2.1.2.1)
PP_0322 -0.0
PP_0671 N.D.
PP_0672 -1.3

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information