MetaCyc Pathway: L-leucine degradation III in Pseudomonas putida KT2440

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Reactions and Genes Formaldehyde 0.03125 vol%
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Branched-chain-amino-acid transaminase:
L-leucine + 2-oxoglutarate→4-methyl-2-oxopentanoate + L-glutamate (EC 2.6.1.42; 2.6.1.6)
PP_3511 -0.4
Branched-chain-2-oxoacid decarboxylase:
4-methyl-2-oxopentanoate + H+→3-methylbutanal + CO2 (EC 4.1.1.72)
No genes
Alcohol dehydrogenase (in reverse):
3-methylbutanal + NADH + H+→3-methylbutanol + NAD+ (EC 1.1.1.1)
PP_1616 -4.4
PP_2049 +0.4
PP_2426 -0.0
PP_2650 +0.3
PP_2803 -0.1
PP_3839 -0.1
PP_4760 +0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information