MetaCyc Pathway: (S)-propane-1,2-diol degradation in Escherichia coli BW25113
| Reactions and Genes | 3-methyl-2-butenol 1.25 vol% |
|---|---|
| remove | |
| Propanediol dehydratase: (S)-propane-1,2-diol→1-propanal + H2O (EC 4.2.1.28) | |
| No genes | |
| 1-propanal + coenzyme A + NAD+→propanoyl-CoA + NADH + H+ (EC 1.2.1.87) | |
| No genes | |
| Alcohol dehydrogenase (in reverse): 1-propanal + NADH + H+→propan-1-ol + NAD+ (EC 1.1.1.1) | |
| b0325 (yahK) | +0.2 |
| b0356 (frmA) | -1.7 |
| b1241 (adhE) | +0.0 |
| b1478 (adhP) | -0.2 |
| b3253 (yhdH) | +0.0 |
| b4269 (yjgB) | +0.1 |
| b3589 (yiaY) | +0.0 |
| propanoyl-CoA + phosphate→propanoyl phosphate + coenzyme A (EC 2.3.1.222) | |
| b2297 (pta) | -1.7 |
| Acetate kinase (in reverse): propanoyl phosphate + ADP→propanoate + ATP (EC 2.7.2.1; 2.7.2.14; 2.7.2.15; 2.7.2.7) | |
| b2296 (ackA) | N.D. |
| b3115 (tdcD) | +0.1 |
Links:
- Pathway details at MetaCyc
- Fitness data for 10 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information