MetaCyc Pathway: L-tyrosine degradation III in Pseudomonas putida KT2440

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Reactions and Genes L-tyrosine 5 mM (C)
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Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine (EC 2.6.1.58)
No genes
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
PP_0486 -0.1
PP_0858 -0.1
PP_0967 -0.6
PP_1109 +0.1
PP_1872 -3.4
PP_1972 -0.6
PP_2642 +0.1
PP_2948 -0.0
PP_3544 -0.1
PP_3590 -2.4
PP_3750 -0.1
PP_3786 -0.2
PP_4197 -1.1
PP_5275 -0.1
PP_5342 +0.0
4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2 (EC 4.1.1.80)
No genes
Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+ (EC 1.1.1.1)
PP_1616 -0.1
PP_2049 +0.0
PP_2426 +0.3
PP_2650 -0.8
PP_2803 +0.2
PP_3839 +0.0
PP_4760 +0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information