MetaCyc Pathway: L-tyrosine degradation IV (to 4-methylphenol) in Pseudomonas putida KT2440

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Reactions and Genes L-tyrosine 5 mM (C)
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Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
PP_0486 -0.1
PP_0858 -0.1
PP_0967 -0.6
PP_1109 +0.1
PP_1872 -3.4
PP_1972 -0.6
PP_2642 +0.1
PP_2948 -0.0
PP_3544 -0.1
PP_3590 -2.4
PP_3750 -0.1
PP_3786 -0.2
PP_4197 -1.1
PP_5275 -0.1
PP_5342 +0.0
4-hydroxyphenylpyruvate oxidase:
2 3-(4-hydroxyphenyl)pyruvate + dioxygen→2 (4-hydroxyphenyl)acetate + 2 CO2 (EC 1.2.3.13)
No genes
4-hydroxyphenylacetate decarboxylase:
(4-hydroxyphenyl)acetate + H+→4-methylphenol + CO2 (EC 4.1.1.83)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information