MetaCyc Pathway: superpathway of anaerobic energy metabolism (invertebrates) in Pseudomonas putida KT2440

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Reactions and Genes mixed (C)s Trisodium citrate 10 mM and 4-azido-L-phenylalanine 10 mM
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Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + GDP→oxaloacetate + GTP (EC 4.1.1.32)
No genes
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
PP_1362 +0.4
PP_4301 +0.1
Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + IDP→oxaloacetate + ITP (EC 4.1.1.32)
No genes
Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)
PP_0817 +0.1
PP_1872 -0.3
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
PP_0654 +0.1
PP_2835 +0.0
Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)
No genes
Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1; 5.1.1.10)
PP_3722 -0.2
PP_5269 N.D.
Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)
PP_0486 -0.1
PP_0858 -0.0
PP_1109 +0.9
PP_1872 -0.3
PP_2642 -0.1
PP_2948 -0.0
PP_3544 -0.0
PP_3750 +0.2
PP_3786 -0.2
PP_4197 -4.9
PP_5275 +0.0
PP_5342 +0.1
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
PP_0897 N.D.
PP_0944 +0.1
PP_1755 -0.1
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
PP_0338 N.D.
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
PP_0154 +0.4
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
No genes
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
PP_4185 N.D.
PP_4186 N.D.
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
PP_1607 N.D.
PP_1996 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information