MetaCyc Pathway: 4-hydroxy-2-nonenal detoxification in Pseudomonas putida KT2440

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Reactions and Genes mixed (C)s Trisodium citrate 10 mM and L-Phenylalanine 5 mM
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Glutathione transferase:
4-hydroxy-2-nonenal + glutathione→(glutathion-S-yl)-4-hydroxy-2-nonenal (EC 2.5.1.18)
PP_0183 +0.1
PP_1162 -0.1
PP_1347 -0.5
PP_1821 -0.1
PP_2474 -0.1
PP_2536 +0.2
PP_2933 +0.2
PP_3742 -0.1
PP_3998 -0.2
PP_4104 -0.0
PP_4554 N.D.
PP_4619 -3.2
(glutathion-S-yl)-4-hydroxy-2-nonenal + H2O→S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine + L-glutamate (EC 3.4.19.13)
No genes
S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine + H2O→S-(4-hydroxy-nonenal-3-yl)-L-cysteine + glycine (EC 3.4.13.23)
No genes
Cysteine-S-conjugate N-acetyltransferase:
S-(4-hydroxy-nonenal-3-yl)-L-cysteine + acetyl-CoA→4-hydroxy-2-nonenal-N-acetyl-L-cysteine + coenzyme A + H+ (EC 2.3.1.80)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information