MetaCyc Pathway: lupanine biosynthesis in Escherichia coli BW25113

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Reactions and Genes LB + carbenicillin regrowth after 48hr
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Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
b0186 (ldcC) +0.1
b4131 (cadA) -1.1
3 cadaverine + 4 pyruvate→17-oxosparteine + 4 L-alanine + H+ + 3 H2O
No genes
17-oxosparteine→lupanine
No genes
lupanine→13-hydroxylupanine
No genes
13-hydroxylupinine O-tigloyltransferase:
13-hydroxylupanine + (E)-2-methylcrotonoyl-CoA→13-[(E)-2-methylcrotonoyl]oxylupanine + coenzyme A (EC 2.3.1.93)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information