MetaCyc Pathway: L-lysine degradation I in Escherichia coli BW25113

Reactions and Genes	LB + carbenicillin regrowth after 48hr
Lysine decarboxylase: L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
b0186 (ldcC)	+0.1
b4131 (cadA)	-1.0
Putrescine aminotransferase: cadaverine + 2-oxoglutarate→5-aminopentanal + L-glutamate (EC 2.6.1.82)
b3073 (ygjG)	+0.0
Aminobutyraldehyde dehydrogenase: 5-aminopentanal + NAD+ + H2O→5-aminopentanoate + NADH + 2 H+ (EC 1.2.1.19)
b1444 (ydcW)	+0.1
5-aminovalerate transaminase: 2-oxoglutarate + 5-aminopentanoate→glutarate semialdehyde + L-glutamate (EC 2.6.1.48)
b1302 (puuE)	-0.1
b2662 (gabT)	+0.0
Glutarate-semialdehyde dehydrogenase: glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+ (EC 1.2.1.20)
b1525 (b1525)	-0.1
b2661 (gabD)	-0.0
2-oxoglutarate + glutarate + dioxygen→(S)-2-hydroxyglutarate + CO2 + succinate (EC 1.14.11.64)
b2659 (b2659)	-1.1
(S)-2-hydroxyglutarate + an electron-transfer quinone→2-oxoglutarate + an electron-transfer quinol (EC 1.1.5.13)
b2660 (ygaF)	+0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information