MetaCyc Pathway: L-alanine degradation VI (reductive Stickland reaction) in Escherichia coli BW25113
| Reactions and Genes | carbon source D-Glucose 20mM |
|---|---|
| remove | |
| Alanine transaminase: L-alanine + 2-oxoglutarate→pyruvate + L-glutamate (EC 2.6.1.2) | |
| b2290 (yfbQ) | -1.6 |
| b2379 (yfdZ) | -0.4 |
| D-lactate dehydrogenase (in reverse): pyruvate + NADH + H+→(R)-lactate + NAD+ (EC 1.1.1.28) | |
| b1380 (ldhA) | +0.6 |
| b2133 (dld) | -0.2 |
| Propionate CoA-transferase: (R)-lactate + propanoyl-CoA→(R)-lactoyl-CoA + propanoate (EC 2.8.3.1) | |
| No genes | |
| Lactoyl-CoA dehydratase: (R)-lactoyl-CoA→acryloyl-CoA + H2O (EC 4.2.1.54) | |
| No genes | |
| acryloyl-CoA + NADH + H+→propanoyl-CoA + NAD+ (EC 1.3.1.95) | |
| No genes | |
| Propionate CoA-transferase (in reverse): propanoyl-CoA + acetate→propanoate + acetyl-CoA (EC 2.8.3.1) | |
| No genes | |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information