MetaCyc Pathway: uracil degradation III in Agrobacterium fabrum C58

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Reactions and Genes Orotic (N)
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uracil + FMNH2 + NADH + dioxygen→(Z)-3-ureidoacrylate + FMN + NAD+ + H+ + H2O (EC 1.14.99.46)
Atu2500 -2.4
(Z)-3-ureidoacrylate + H2O→carbamate + (Z)-3-aminoacrylate + H+ (EC 3.5.1.110)
Atu2499 -2.4
carbamate + 2 H+→CO2 + ammonium (spontaneous) (EC 3.5.1.110; 3.5.1.20; 3.5.1.54; 4.2.1.104)
Atu3912 +0.0
Atu4275 -0.1
Atu4276 +0.0
(Z)-3-aminoacrylate + H+ + H2O→3-oxopropanoate + ammonium (spontaneous)
Atu2498 -1.9
3-oxopropanoate + NADPH + H+→3-hydroxypropanoate + NADP+ (EC 1.1.1.298)
Atu2496 -2.2
Atu4280 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information