MetaCyc Pathway: pyruvate fermentation to butanol II (engineered) in Agrobacterium fabrum C58

Reactions and Genes	L-Pipecolic Acid (N)
Acetyl-CoA C-acyltransferase: 2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
Atu0502	+0.0
Atu2769	-1.9
Atu3475	-0.0
Atu4549	-0.1
Atu4823	-0.1
3-hydroxyacyl-CoA dehydrogenase (in reverse): acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
Atu0503	-0.2
Atu1415	+0.2
Atu3597	-1.5
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
Atu0733	+0.0
Atu1417	-0.1
Trans-2-enoyl-CoA reductase (NAD(+)) (in reverse): crotonyl-CoA + NADH + H+→butanoyl-CoA + NAD+ (EC 1.3.1.44)
Atu3474	-0.0
Butanal dehydrogenase (in reverse): butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information