MetaCyc Pathway: gondoate biosynthesis (anaerobic) in Agrobacterium fabrum C58

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Reactions and Genes spermidine (N)
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Beta-ketoacyl-acyl-carrier-protein synthase II:
an oleoyl-[acp] + a malonyl-[acp] + H+→an (11Z)-3-oxo-icos-11-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.1
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an (11Z)-3-oxo-icos-11-enoyl-[acp][cytosol] + NADPH[cytosol] + H+[cytosol]→a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol] + NADP+[cytosol] (EC 1.1.1.100)
Atu0705 +0.0
Atu0990 -0.0
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.2
Atu2042 +0.1
Atu3051 +0.0
Atu3074 -0.2
Atu3333 -0.0
Atu3531 -0.0
Atu3813 -0.0
Atu4220 +0.1
Atu4325 -0.0
Atu4595 +0.1
Atu4821 -0.1
Atu4877 +0.1
Atu5122 +1.7
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.2
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,11Z)-3-hydroxy-icos-11-enoyl-[acp][cytosol]→a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + H2O[cytosol] (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,11Z)-icosa-2,11-dienoyl-[acp][cytosol] + NADH[cytosol] + H+[cytosol]→a gondoyl-[acp][cytosol] + NAD+[cytosol] (EC 1.3.1.9)
Atu0149 +0.1
Atu0757 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information