MetaCyc Pathway: palmitate biosynthesis III in Agrobacterium fabrum C58

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Reactions and Genes spermidine (N)
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3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an acetoacetyl-[acp] + NADPH + H+→a (3R)-3-hydroxybutanoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxybutanoyl-[acp]→a (2E)-but-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-but-2-enoyl-[acp] + NADPH + H+→a butanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Atu5181 -0.1
Atu5185 +0.4
Atu5391 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a butanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxohexanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxohexanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyhexanoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyhexanoyl-[acp]→a (2E)-hex-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-hex-2-enoyl-[acp] + NADPH + H+→a hexanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Atu5181 -0.1
Atu5185 +0.4
Atu5391 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a hexanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxooctanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxooctanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyoctanoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyoctanoyl-[acp]→a (2E)-oct-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-oct-2-enoyl-[acp] + NADPH + H+→an octanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Atu5181 -0.1
Atu5185 +0.4
Atu5391 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
an octanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxodecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxodecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxydecanoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydecanoyl-[acp]→a (2E)-dec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-dec-2-enoyl-[acp] + NADPH + H+→a decanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Atu5181 -0.1
Atu5185 +0.4
Atu5391 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a decanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxododecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxododecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxydodecanoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydodecanoyl-[acp]→a (2E)-dodec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-dodec-2-enoyl-[acp] + NADPH + H+→a dodecanoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Atu5181 -0.1
Atu5185 +0.4
Atu5391 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a dodecanoyl-[acp] + a malonyl-[acp] + H+→a 3-oxotetradecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxotetradecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxytetradecanoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxytetradecanoyl-[acp]→a (2E)-tetradec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-tetradec-2-enoyl-[acp] + NADPH + H+→a myristoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Atu5181 -0.1
Atu5185 +0.4
Atu5391 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a myristoyl-[acp] + a malonyl-[acp] + H+→a 3-oxohexadecanoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a 3-oxohexadecanoyl-[acp] + NADPH + H+→a (3R)-3-hydroxyhexadecanoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxyhexadecanoyl-[acp]→a (2E)-hexadec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (in reverse):
a (2E)-hexadec-2-enoyl-[acp] + NADPH + H+→a palmitoyl-[acp] + NADP+ (EC 1.3.1.10; 1.3.1.104; 1.3.1.39)
Atu5181 -0.1
Atu5185 +0.4
Atu5391 N.D.
Oleoyl-[acyl-carrier-protein] hydrolase:
a palmitoyl-[acp] + H2O→palmitate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
Long-chain-fatty-acid--CoA ligase:
palmitate + ATP + coenzyme A→palmitoyl-CoA + AMP + diphosphate (EC 6.2.1.3)
Atu0405 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information