MetaCyc Pathway: superpathway of unsaturated fatty acids biosynthesis (E. coli) in Agrobacterium fabrum C58

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Reactions and Genes spermidine (N)
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3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R)-3-hydroxydecanoyl-[acp]→a (2E)-dec-2-enoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Trans-2-decenoyl-[acyl-carrier-protein] isomerase:
a (2E)-dec-2-enoyl-[acp]→a (3Z)-dec-3-enoyl-[acp] (EC 5.3.3.14)
Atu0151 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a (3Z)-dec-3-enoyl-[acp] + a malonyl-[acp] + H+→a (5Z)-3-oxododec-5-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a (5Z)-3-oxododec-5-enoyl-[acp] + NADPH + H+→a (3R,5Z)-3-hydroxydodec-5-enoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,5Z)-3-hydroxydodec-5-enoyl-[acp]→a (2E,5Z)-dodeca-3,5-dienoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,5Z)-dodeca-3,5-dienoyl-[acp] + NADH + H+→a (5Z)-dodec-5-enoyl-[acp] + NAD+ (EC 1.3.1.9)
Atu0149 -0.4
Atu0757 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a (5Z)-dodec-5-enoyl-[acp] + a malonyl-[acp] + H+→a (7Z)-3-oxotetradec-7-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a (7Z)-3-oxotetradec-7-enoyl-[acp] + NADPH + H+→a (3R,7Z)-3-hydroxytetradec-7-enoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,7Z)-3-hydroxytetradec-7-enoyl-[acp]→a (2E,7Z)-tetradeca-2,7-dienoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,7Z)-tetradeca-2,7-dienoyl-[acp] + NADH + H+→a (7Z)-tetradec-7-enoyl-[acp] + NAD+ (EC 1.3.1.9)
Atu0149 -0.4
Atu0757 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a (7Z)-tetradec-7-enoyl-[acp] + a malonyl-[acp] + H+→a (9Z)-3-oxohexadec-9-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179; 2.3.1.41)
Atu0150 N.D.
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
a (9Z)-3-oxohexadec-9-enoyl-[acp] + NADPH + H+→a (3R,9Z)-3-hydroxyhexadec-9-enoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,9Z)-3-hydroxyhexadec-9-enoyl-[acp]→a (2E,9Z)-hexadeca-2,9-dienoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,9Z)-hexadeca-2,9-dienoyl-[acp] + NADH + H+→a palmitoleoyl-[acp] + NAD+ (EC 1.3.1.9)
Atu0149 -0.4
Atu0757 N.D.
Beta-ketoacyl-acyl-carrier-protein synthase II:
a palmitoleoyl-[acp] + a malonyl-[acp] + H+→an (11Z)-3-oxooctadec-11-enoyl-[acp] + a soluble [acyl-carrier protein] + CO2 (EC 2.3.1.179)
Atu1097 N.D.
Atu1596 N.D.
Atu1597 N.D.
Atu4216 -0.0
Oleoyl-[acyl-carrier-protein] hydrolase:
a palmitoleoyl-[acp] + H2O→palmitoleate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
an (11Z)-3-oxooctadec-11-enoyl-[acp] + NADPH + H+→a (3R,11Z)-3-hydroxyoctadec-11-enoyl-[acp] + NADP+ (EC 1.1.1.100)
Atu0705 +0.1
Atu0990 -0.2
Atu1095 N.D.
Atu1255 +0.1
Atu1338 +0.1
Atu2042 +0.2
Atu3051 -0.1
Atu3074 -0.1
Atu3333 -0.2
Atu3531 +0.1
Atu3813 -0.2
Atu4220 -0.0
Atu4325 +0.1
Atu4595 -0.1
Atu4821 -0.1
Atu4877 -0.4
Atu5122 +1.3
Atu5214 N.D.
Atu5250 N.D.
Atu5438 +0.1
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
a (3R,11Z)-3-hydroxyoctadec-11-enoyl-[acp]→a (2E,11Z)-octadeca-2,11-dienoyl-[acp] + H2O (EC 4.2.1.59)
Atu0151 N.D.
Atu1383 N.D.
Atu1599 N.D.
Enoyl-[acyl-carrier-protein] reductase (NADH) (in reverse):
a (2E,11Z)-octadeca-2,11-dienoyl-[acp] + NADH + H+→a cis-vaccenoyl-[acp] + NAD+ (EC 1.3.1.9)
Atu0149 -0.4
Atu0757 N.D.
Oleoyl-[acyl-carrier-protein] hydrolase:
a cis-vaccenoyl-[acp] + H2O→cis-vaccenate + a soluble [acyl-carrier protein] + H+ (EC 3.1.2.14)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information