MetaCyc Pathway: ketolysis in Pseudomonas fluorescens GW456-L13

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Reactions and Genes L-Isoleucine (N)
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3-hydroxybutyrate dehydrogenase:
(R)-3-hydroxybutanoate + NAD+→acetoacetate + NADH + H+ (EC 1.1.1.30)
PfGW456L13_2873 -0.1
3-oxoacid CoA-transferase:
acetoacetate + succinyl-CoA→acetoacetyl-CoA + succinate (EC 2.8.3.5)
No genes
Acetyl-CoA C-acyltransferase (in reverse):
acetoacetyl-CoA + coenzyme A→2 acetyl-CoA (EC 2.3.1.16; 2.3.1.9)
PfGW456L13_2157 +0.1
PfGW456L13_2411 -0.2
PfGW456L13_2430 -0.1
PfGW456L13_2498 -0.1
PfGW456L13_2538 -0.0
PfGW456L13_2539 -0.3
PfGW456L13_29 -0.0
PfGW456L13_2982 -2.4
PfGW456L13_3394 +0.0
PfGW456L13_3408 -0.1
PfGW456L13_4040 -0.1
PfGW456L13_4147 +0.2
PfGW456L13_4590 +0.8

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information