MetaCyc Pathway: superpathway of methylglyoxal degradation in Agrobacterium fabrum C58

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Reactions and Genes 2,6-diaminopimelic (N)
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Methylglyoxal reductase (NADPH-dependent) (in reverse):
methylglyoxal + NADPH + H+→(S)-lactaldehyde + NADP+ (EC 1.1.1.283)
No genes
Lactoylglutathione lyase (in reverse):
methylglyoxal + glutathione→(R)-S-lactoylglutathione (EC 4.4.1.5)
Atu1802 -0.1
Atu2456 -0.3
Aldehyde reductase (in reverse):
methylglyoxal + NADPH + H+→hydroxyacetone + NADP+ (EC 1.1.1.21)
Atu0867 -0.0
Atu1524 -0.0
Atu2032 -0.2
Hydroxyacylglutathione hydrolase:
(R)-S-lactoylglutathione + H2O→(R)-lactate + glutathione + H+ (EC 3.1.2.6)
Atu2201 +0.1
Atu3613 +0.1
Atu3614 +0.2
Atu3925 +0.1
Atu5518 +0.1
Lactaldehyde dehydrogenase:
(S)-lactaldehyde + NAD+ + H2O→(S)-lactate + NADH + 2 H+ (EC 1.2.1.22)
Atu3485 -0.4
Atu4153 -1.8
Atu5204 -0.0
hydroxyacetone + NADH + H+→(S)-propane-1,2-diol + NAD+
No genes
(S)-lactate[in] + an electron-transfer quinone→pyruvate[in] + an electron-transfer quinol (EC 1.1.5.M6)
Atu2318 +0.1
(R)-lactate[in] + an electron-transfer quinone→pyruvate[in] + an electron-transfer quinol (EC 1.1.5.12)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information