MetaCyc Pathway: aspartate superpathway in Agrobacterium fabrum C58

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Reactions and Genes L-Phenylalanine (N)
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Aspartate transaminase (in reverse):
oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate
(EC 2.6.1.1)
Atu0235 -0.0
Atu0529 -1.1
Atu1589 -0.7
Atu1848 -0.7
Atu2196 N.D.
Atu4266 +0.1
Atu4278 -0.0
Aspartate kinase:
L-aspartate + ATP→L-aspartyl-4-phosphate + ADP
(EC 2.7.2.4)
Atu4172 N.D.
L-aspartate oxidase:
L-aspartate + dioxygen→2-iminosuccinate + hydrogen peroxide + H+
(EC 1.4.3.16)
Atu4097 -0.0
Aspartate-semialdehyde dehydrogenase (in reverse):
L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate
(EC 1.2.1.11)
Atu2490 N.D.
Quinolinate synthase:
2-iminosuccinate + glycerone phosphate→quinolinate + phosphate + 2 H2O
(EC 2.5.1.72)
Atu4098 -0.2
L-aspartate 4-semialdehyde + pyruvate→(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H+ + H2O (EC 4.3.3.7)
Atu0899 +0.0
Atu1024 N.D.
Atu2503 -0.0
Atu3960 -0.0
Atu4189 -0.1
Atu5067 +0.0
Atu5394 N.D.
Atu5398 N.D.
Atu5457 +0.5
Homoserine dehydrogenase (in reverse):
L-aspartate 4-semialdehyde + NAD(P)H + H+→L-homoserine + NAD(P)+
(EC 1.1.1.3)
Atu1588 -1.9
Atu3161 -0.0
Nicotinate-nucleotide diphosphorylase (carboxylating) (in reverse):
quinolinate + 2 H+ + 5-phospho-α-D-ribose 1-diphosphate→β-nicotinate D-ribonucleotide + CO2 + diphosphate
(EC 2.4.2.19)
Atu4096 -0.2
Homoserine kinase:
L-homoserine + ATP→O-phospho-L-homoserine + ADP + H+
(EC 2.7.1.39)
Atu0775 N.D.
Homoserine O-succinyltransferase:
L-homoserine + succinyl-CoA→O-succinyl-L-homoserine + coenzyme A
(EC 2.3.1.46)
Atu2718 -1.8
Nicotinate-nucleotide adenylyltransferase:
β-nicotinate D-ribonucleotide + ATP + H+→nicotinate adenine dinucleotide + diphosphate
(EC 2.7.7.18)
Atu2778 N.D.
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+→(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ + H2O (EC 1.17.1.8)
Atu0183 N.D.
NAD(+) synthase (glutamine-hydrolyzing):
nicotinate adenine dinucleotide + ATP + L-glutamine + H2O→NAD+ + AMP + L-glutamate + diphosphate + H+
(EC 6.3.5.1)
Atu1657 N.D.
NAD(+) synthase:
nicotinate adenine dinucleotide + ammonium + ATP→NAD+ + AMP + diphosphate + H+
(EC 6.3.1.5)
Atu1657 N.D.
Cystathionine gamma-synthase:
O-succinyl-L-homoserine + L-cysteine→L-cystathionine + H+ + succinate
(EC 2.5.1.48)
Atu0432 -2.5
Atu1250 +0.1
Atu1251 +0.1
Atu3175 +0.2
Atu3806 -0.0
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase:
(S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2ON-succinyl-2-amino-6-ketopimelate + coenzyme A
(EC 2.3.1.117)
Atu0371 N.D.
Threonine synthase:
O-phospho-L-homoserine + H2O→L-threonine + phosphate
(EC 4.2.3.1)
Atu0787 N.D.
Cysteine-S-conjugate beta-lyase:
L-cystathionine + H2O→L-homocysteine + ammonium + pyruvate
(EC 4.4.1.13)
No genes
Succinyldiaminopimelate transaminase (in reverse):
N-succinyl-2-amino-6-ketopimelate + L-glutamateN-succinyl-L,L-2,6-diaminopimelate + 2-oxoglutarate
(EC 2.6.1.17)
Atu0428 N.D.
5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase:
L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate→L-methionine + tetrahydropteroyl tri-L-glutamate
(EC 2.1.1.14)
Atu3823 -0.1
Methionine synthase:
L-homocysteine + a 5-methyltetrahydrofolate→L-methionine + a tetrahydrofolate
(EC 2.1.1.13)
Atu2155 -1.0
Succinyl-diaminopimelate desuccinylase:
N-succinyl-L,L-2,6-diaminopimelate + H2O→L,L-diaminopimelate + succinate
(EC 3.5.1.18)
Atu0370 N.D.
Atu5479 +0.1
Diaminopimelate epimerase:
L,L-diaminopimelate→meso-diaminopimelate
(EC 5.1.1.7)
Atu0600 N.D.
Atu2695 N.D.
Atu4835 -0.0
Methionine adenosyltransferase:
L-methionine + ATP + H2OS-adenosyl-L-methionine + diphosphate + phosphate
(EC 2.5.1.6)
Atu0362 N.D.
Diaminopimelate decarboxylase:
meso-diaminopimelate + H+→L-lysine + CO2
(EC 4.1.1.20)
Atu1673 +0.2
Atu3601 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information