MetaCyc Pathway: superpathway of L-phenylalanine biosynthesis in Agrobacterium fabrum C58

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Reactions and Genes L-Phenylalanine (N)
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3-deoxy-7-phosphoheptulonate synthase:
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O→3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate
(EC 2.5.1.54)
Atu1610 N.D.
3-dehydroquinate synthase:
3-deoxy-D-arabino-heptulosonate 7-phosphate→3-dehydroquinate + phosphate
(EC 4.2.3.4)
Atu3625 N.D.
3-dehydroquinate dehydratase:
3-dehydroquinate→3-dehydroshikimate + H2O
(EC 4.2.1.10)
Atu1332 N.D.
Atu1426 N.D.
Atu4531 +0.0
Shikimate dehydrogenase (in reverse):
3-dehydroshikimate + NADPH + H+→shikimate + NADP+
(EC 1.1.1.25)
Atu0003 N.D.
Atu4295 +0.1
Atu4532 +0.3
Shikimate kinase:
shikimate + ATP→shikimate 3-phosphate + ADP + H+
(EC 2.7.1.71)
Atu3626 N.D.
3-phosphoshikimate 1-carboxyvinyltransferase:
shikimate 3-phosphate + phosphoenolpyruvate→5-enolpyruvoyl-shikimate 3-phosphate + phosphate
(EC 2.5.1.19)
Atu0642 N.D.
Chorismate synthase:
5-enolpyruvoyl-shikimate 3-phosphate→chorismate + phosphate
(EC 4.2.3.5)
Atu0754 N.D.
Chorismate mutase:
chorismate→prephenate
(EC 5.4.99.5)
Atu2698 N.D.
Prephenate dehydratase:
prephenate + H+→3-phenyl-2-oxopropanoate + CO2 + H2O
(EC 4.2.1.51)
Atu0099 -0.0
Aspartate transaminase (in reverse):
3-phenyl-2-oxopropanoate + L-glutamate→L-phenylalanine + 2-oxoglutarate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
Atu0235 -0.0
Atu0529 -1.1
Atu1011 +0.0
Atu1589 -0.7
Atu1848 -0.7
Atu2015 -0.2
Atu2196 N.D.
Atu3612 N.D.
Atu4266 +0.1
Atu4278 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information