MetaCyc Pathway: L-histidine degradation I in Pseudomonas fluorescens GW456-L13

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Reactions and Genes L-Histidine (N)
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Histidine ammonia-lyase:
L-histidine→urocanate + ammonium (EC 4.3.1.3)
PfGW456L13_242 +0.2
PfGW456L13_320 -2.3
PfGW456L13_321 +0.1
Urocanate hydratase (in reverse):
urocanate + H2O→4-imidazolone-5-propanoate (EC 4.2.1.49)
PfGW456L13_326 -1.7
Imidazolonepropionase:
4-imidazolone-5-propanoate + H2O→N-formimino-L-glutamate (EC 3.5.2.7)
PfGW456L13_317 -3.7
Formimidoylglutamase:
N-formimino-L-glutamate + H2O→L-glutamate + formamide (EC 3.5.3.8)
PfGW456L13_316 -4.8

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information